David C Dale Selected Research

Cyclic neutropenia

12/2017	Long-Term Effects of G-CSF Therapy in Cyclic Neutropenia.
1/2015	The diversity of mutations and clinical outcomes for ELANE-associated neutropenia.
11/2012	Repeated lentivirus-mediated granulocyte colony-stimulating factor administration to treat canine cyclic neutropenia.
1/2011	Cyclic and chronic neutropenia.
4/2006	An adult dog with cyclic neutropenia treated by lentivirus- mediated delivery of granulocyte colony-stimulating factor.
9/2003	Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery.
9/2003	Molecular basis and therapy of disorders associated with chronic neutropenia.
8/2002	Cloning and sequencing of the canine neutrophil elastase cDNA.
4/2002	Cyclic neutropenia.

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David C Dale Research Topics

Disease

34	Neutropenia 12/2022 - 01/2002
23	Neoplasms (Cancer) 12/2022 - 01/2002
20	Infections 01/2020 - 01/2002
18	Autosomal Recessive 3 Severe Congenital Neutropenia 01/2022 - 12/2002
17	Febrile Neutropenia 10/2022 - 01/2002
12	severe chronic Neutropenia 12/2022 - 06/2006
10	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 02/2003
9	Cyclic neutropenia 12/2017 - 04/2002
9	Breast Neoplasms (Breast Cancer) 01/2015 - 07/2003
6	Non-Hodgkin Lymphoma (Lymphosarcoma) 10/2022 - 07/2003
5	Lymphoma (Lymphomas) 04/2014 - 07/2007
4	Lung Neoplasms (Lung Cancer) 10/2022 - 10/2007
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 07/2013 - 06/2010
2	WHIM syndrome 12/2020 - 11/2011
2	Splenomegaly 01/2019 - 07/2013
2	Fever (Fevers) 01/2019 - 01/2017
2	Pain (Aches) 01/2019 - 01/2018
2	Pneumonia (Pneumonitis) 01/2018 - 01/2002
2	Chromosome Aberrations (Chromosome Abnormalities) 07/2013 - 07/2006
2	Ovarian Neoplasms (Ovarian Cancer) 04/2013 - 10/2007
2	Body Weight (Weight, Body) 11/2012 - 12/2006
2	Sepsis (Septicemia) 07/2010 - 06/2006
2	Leukemia 06/2006 - 05/2006
2	Leukocytosis (Pleocytosis) 04/2004 - 10/2003
1	Autoimmune Diseases (Autoimmune Disease) 12/2022
1	Aplastic Anemia (Anemia, Hypoplastic) 12/2022
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Cellulitis 01/2019
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Barth Syndrome 01/2019
1	Glycogen Storage Disease IB 01/2019
1	Inflammation (Inflammations) 05/2015
1	Chronic Obstructive Pulmonary Disease (COPD) 05/2015
1	Prostatic Neoplasms (Prostate Cancer) 09/2014
1	Lipomatosis 04/2014
1	Heart Failure 10/2013
1	Venous Thromboembolism 10/2013
1	Stomach Neoplasms (Stomach Cancer) 10/2013
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 10/2013
1	Cytopenia 07/2013
1	Mycoses (Diseases, Fungus) 07/2013
1	Ovarian Epithelial Carcinoma 04/2013
1	Second Primary Neoplasms (Neoplasms, Second) 06/2010
1	GATA2 Deficiency 01/2009
1	Urogenital Neoplasms 10/2007
1	Colorectal Neoplasms (Colorectal Cancer) 10/2007
1	Musculoskeletal Pain 07/2007

Drug/Important Bio-Agent (IBA)

37	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2022 - 01/2002
12	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2020 - 04/2002
9	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 01/2015 - 01/2002
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 07/2006
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017 - 12/2003
4	plerixafor FDA Link 11/2011 - 10/2003
4	Granulocyte Colony-Stimulating Factor Receptors (G-CSF Receptor)IBA 08/2008 - 05/2006
3	Filgrastim (Neupogen)FDA Link 10/2022 - 11/2003
3	CytokinesIBA 01/2020 - 01/2002
3	Pancreatic Elastase (Elastase)IBA 10/2017 - 12/2002
2	2- hydroxy- N,N- dimethyl- 3- (2- ((1- (5- methylfuran- 2- yl)propyl)amino)- 3,4- dioxocyclobut- 1- enylamino)benzamideIBA 05/2015 - 04/2015
2	PlatinumIBA 04/2013 - 10/2007
2	Cytochromes c (Cytochrome c)IBA 03/2012 - 05/2004
2	Hemoglobins (Hemoglobin)IBA 12/2006 - 12/2003
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2002 - 01/2002
1	Biosimilar PharmaceuticalsIBA 10/2022
1	pegfilgrastim (Neulasta)FDA Link 10/2022
1	Endopeptidase ClpIBA 01/2022
1	mavorixaforIBA 12/2020
1	RibonucleoproteinsIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2019
1	SalicylatesIBA 01/2019
1	Prednisone (Sone)FDA LinkGeneric 01/2019
1	Mesalamine (Mesalazine)FDA LinkGeneric 01/2019
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2019
1	Peptide Hydrolases (Proteases)FDA Link 10/2017
1	Dihydrotachysterol (AT 10)IBA 05/2015
1	Cytokine Receptors (Cytokine Receptor)IBA 05/2015
1	Caspase 3 (Caspase-3)IBA 03/2012
1	CaspasesIBA 03/2012
1	SerpinsIBA 07/2011
1	Serine Proteases (Serine Protease)IBA 07/2011
1	STAT5 Transcription FactorIBA 01/2009
1	Alkaline PhosphataseIBA 10/2007
1	NitrogenIBA 10/2007
1	Urea (Carbamide)FDA LinkGeneric 10/2007
1	AnthracyclinesIBA 10/2007

Therapy/Procedure

31	Drug Therapy (Chemotherapy) 10/2022 - 01/2002
19	Therapeutics 12/2022 - 01/2002
5	Drug Tapering 04/2014 - 01/2004
4	Adjuvant Chemotherapy 06/2007 - 12/2003
3	Length of Stay 09/2014 - 05/2006
3	Injections 11/2012 - 09/2003
2	Subcutaneous Injections 01/2011 - 04/2004
2	Transplantation 05/2006 - 11/2002
1	Autologous Transplantation 01/2020
1	Gastrostomy 01/2019
1	Liver Transplantation 01/2019
1	Combination Drug Therapy (Combination Chemotherapy) 09/2014
1	Erythrocyte Transfusion 10/2013
1	Hematopoietic Stem Cell Transplantation 07/2013
1	Intramuscular Injections 11/2012